|Application ||WB, E|
|Calculated MW||56931 Da|
|Antigen Region||142-169 aa|
|Other Names||Vascular endothelial zinc finger 1, Putative transcription factor DB1, Zinc finger protein 161, VEZF1, DB1, ZNF161|
|Target/Specificity||This VEZF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 142-169 amino acids from the Central region of human VEZF1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||VEZF1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Possible transcription factor. Specifically binds to the CT/GC-rich region of the interleukin-3 promoter and mediates tax transactivation of IL-3.|
|Tissue Location||Ubiquitously expressed. Highest levels in skeletal muscle and kidney.|
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Provided below are standard protocols that you may find useful for product applications.
Transcriptional regulatory proteins containing tandemly repeated zinc finger domains are thought to be involved in both normal and abnormal cellular proliferation and differentiation. ZNF161 is a C2H2-type zinc finger protein (Koyano-Nakagawa et al., 1994 [PubMed 8035792]). See MIM 603971 for general information on zinc finger proteins.
Aitsebaomo, J., et al. J. Biol. Chem. 276(42):39197-39205(2001)
Lebowitz, P.F., et al. Cell Adhes. Commun. 6(4):277-287(1998)
Koyano-Nakagawa, N., et al. Mol. Cell. Biol. 14(8):5099-5107(1994)
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