|Application ||WB, E|
|Calculated MW||31909 Da|
|Antigen Region||9-36 aa|
|Other Names||Postacrosomal sheath WW domain-binding protein, WW domain-binding protein 2-like, WBP2NL, PAWP|
|Target/Specificity||This WBP2NL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 9-36 amino acids from the N-terminal region of human WBP2NL.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||WBP2NL Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May play a role in meotic resumption and pronuclear formation, mediated by a WW domain-signaling pathway during fertilization.|
|Tissue Location||Expressed in testis.|
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Provided below are standard protocols that you may find useful for product applications.
WBP2NL is a sperm-specific WW domain-binding protein that promotes meiotic resumption and pronuclear development during oocyte fertilization (Wu et al., 2007 [PubMed 17289678]).[supplied by OMIM].
Wu, A.T., et al. J. Biol. Chem. 282(16):12164-12175(2007)
Collins, J.E., et al. Genome Biol. 5 (10), R84 (2004) :
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