NXNL1 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
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Primary Accession | Q96CM4 |
Other Accession | NP_612463.1 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 23943 Da |
Antigen Region | 94-121 aa |
Gene ID | 115861 |
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Other Names | Nucleoredoxin-like protein 1, Thioredoxin-like protein 6, NXNL1, TXNL6 |
Target/Specificity | This NXNL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 94-121 amino acids from the Central region of human NXNL1. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | NXNL1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | NXNL1 |
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Synonyms | TXNL6 |
Function | Plays an important role in retinal cone photoreceptor survival (PubMed:25957687). In association with glucose transporter SLC16A1/GLUT1 and BSG, promotes retinal cone survival by enhancing aerobic glycolysis and accelerating the entry of glucose into photoreceptors (PubMed:25957687). May play a role in cone cell viability, slowing down cone degeneration, does not seem to play a role in degenerating rods (By similarity). |
Cellular Location | Cell projection, cilium, photoreceptor outer segment {ECO:0000250|UniProtKB:Q8VC33} |
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Provided below are standard protocols that you may find useful for product applications.
Background
NXNL1 may play a role in cone cell viability, slowing down cone degeneration, does not seem to play a role in degenerating rods (By similarity).
References
Reichman, S., et al. Hum. Mol. Genet. 19(2):250-261(2010)
Bin, J., et al. Hum. Mutat. 30 (7), E737-E746 (2009) :
Wang, X.W., et al. Free Radic. Biol. Med. 45(3):336-344(2008)
Lamesch, P., et al. Genomics 89(3):307-315(2007)
Roni, V., et al. BMC Genomics 8, 42 (2007) :
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