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PPWD1 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q96BP3 |
| Other Accession | Q8CEC6, NP_056157.1 |
| Reactivity | Human |
| Predicted | Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 73575 Da |
| Antigen Region | 236-262 aa |
| Gene ID | 23398 |
|---|---|
| Other Names | Peptidylprolyl isomerase domain and WD repeat-containing protein 1, Spliceosome-associated cyclophilin, PPWD1, KIAA0073 |
| Target/Specificity | This PPWD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 236-262 amino acids from the Central region of human PPWD1. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | PPWD1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | PPWD1 (HGNC:28954) |
|---|---|
| Function | PPIase that catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and may therefore assist protein folding (PubMed:20676357). May be involved in pre-mRNA splicing (PubMed:11991638). |
| Cellular Location | Nucleus. Note=Associated with spliceosomal complexes |
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Provided below are standard protocols that you may find useful for product applications.
Background
Putative peptidylprolyl isomerase (PPIase). PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. May be involved in pre-mRNA splicing.
References
Davis, T.L., et al. FEBS J. 275(9):2283-2295(2008)
Jurica, M.S., et al. RNA 8(4):426-439(2002)
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