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NEO1 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - NEO1 Antibody (Center) AP17802C
    NEO1 Antibody (Center) (Cat. #AP17802c) western blot analysis in mouse spleen tissue lysates (35ug/lane).This demonstrates the NEO1 antibody detected the NEO1 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q92859
Other Accession P97603, P97798, NP_002490.2
Reactivity Human, Mouse
Predicted Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 160017 Da
Antigen Region 657-685 aa
Additional Information
Gene ID 4756
Other Names Neogenin, Immunoglobulin superfamily DCC subclass member 2, NEO1, IGDCC2, NGN
Target/Specificity This NEO1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 657-685 amino acids from the Central region of human NEO1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsNEO1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name NEO1
Synonyms IGDCC2, NGN
Function Multi-functional cell surface receptor regulating cell adhesion in many diverse developmental processes, including neural tube and mammary gland formation, myogenesis and angiogenesis. Receptor for members of the BMP, netrin, and repulsive guidance molecule (RGM) families. Netrin-Neogenin interactions result in a chemoattractive axon guidance response and cell-cell adhesion, the interaction between NEO1/Neogenin and RGMa and RGMb induces a chemorepulsive response.
Cellular Location Cell membrane; Single-pass type I membrane protein
Tissue Location Widely expressed and also in cancer cell lines
Research Areas
Citations (0)

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This gene encodes a cell surface protein that is a member of the immunoglobulin superfamily. The encoded protein consists of four N-terminal immunoglobulin-like domains, six fibronectin type III domains, a transmembrane domain and a C-terminal internal domain that shares homology with the tumor suppressor candidate gene DCC. This protein may be involved in cell growth and differentiation and in cell-cell adhesion. Defects in this gene are associated with cell proliferation in certain cancers. Alternate splicing results in multiple transcript variants. [provided by RefSeq].


Bradford, D., et al. J. Comp. Neurol. 518(16):3237-3253(2010)
Davila, S., et al. Genes Immun. 11(3):232-238(2010)
Zhang, A.S., et al. J. Biol. Chem. 284(34):22580-22589(2009)
Fujita, Y., et al. Cell Death Differ. 15(10):1593-1608(2008)
Zhang, A.S., et al. J. Biol. Chem. 283(25):17494-17502(2008)

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$ 295.00
$ 99.00
Cat# AP17802C
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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