|Application ||WB, E|
|Calculated MW||43072 Da|
|Antigen Region||346-372 aa|
|Other Names||Translocating chain-associated membrane protein 1, TRAM1, TRAM|
|Target/Specificity||This TRAM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 346-372 amino acids from the C-terminal region of human TRAM1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||TRAM1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Stimulatory or required for the translocation of secretory proteins across the ER membrane.|
|Cellular Location||Endoplasmic reticulum membrane; Multi-pass membrane protein|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a multi-pass membrane protein that is part of the mammalian endoplasmic reticulum. The encoded protein influences glycosylation and facilitates the translocation of secretory proteins across the endoplasmic reticulum membrane by regulating which domains of the nascent polypeptide chain are visible to the cytosol during a translocational pause. [provided by RefSeq].
Silva, L.K., et al. Eur. J. Hum. Genet. 18(11):1221-1227(2010)
Han, S., et al. Hum. Immunol. 71(7):727-730(2010)
Mosbruger, T.L., et al. J. Infect. Dis. 201(9):1371-1380(2010)
Rajaraman, P., et al. Cancer Epidemiol. Biomarkers Prev. 19(5):1356-1361(2010)
Rajaraman, P., et al. Cancer Epidemiol. Biomarkers Prev. 18(5):1651-1658(2009)
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