|Application ||WB, E|
|Calculated MW||89099 Da|
|Antigen Region||203-229 aa|
|Other Names||Chromosome alignment-maintaining phosphoprotein 1, Zinc finger protein 828, CHAMP1, C13orf8, CAMP, KIAA1802, ZNF828|
|Target/Specificity||This ZNF828 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 203-229 amino acids from the Central region of human ZNF828.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||ZNF828 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||C13orf8, CAMP, CHAMP, KIAA1802, ZNF828|
|Function||Required for proper alignment of chromosomes at metaphase and their accurate segregation during mitosis. Involved in the maintenance of spindle microtubules attachment to the kinetochore during sister chromatid biorientation. May recruit CENPE and CENPF to the kinetochore.|
|Cellular Location||Nucleus. Chromosome. Chromosome, centromere, kinetochore. Cytoplasm, cytoskeleton, spindle|
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Provided below are standard protocols that you may find useful for product applications.
The function of this protein remains unknown.
Itoh, G., et al. EMBO J. (2010) In press :
Olsen, J.V., et al. Cell 127(3):635-648(2006)
Beausoleil, S.A., et al. Nat. Biotechnol. 24(10):1285-1292(2006)
Beausoleil, S.A., et al. Proc. Natl. Acad. Sci. U.S.A. 101(33):12130-12135(2004)
Dunham, A., et al. Nature 428(6982):522-528(2004)
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