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>   home   >   Products   >   Primary Antibodies   >   Neuroscience   >   NOTUM Antibody (C-term)   

NOTUM Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - NOTUM Antibody (C-term) AP17837b
    NOTUM Antibody (C-term) (Cat. #AP17837b) western blot analysis in MCF-7 cell line lysates (35ug/lane).This demonstrates the NOTUM antibody detected the NOTUM protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q6P988
Other Accession NP_848588.3
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 55699 Da
Antigen Region 353-379 aa
Additional Information
Gene ID 147111
Other Names Protein notum homolog, 3---, NOTUM
Target/Specificity This NOTUM antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 353-379 amino acids from the C-terminal region of human NOTUM.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsNOTUM Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name NOTUM (HGNC:27106)
Function Carboxylesterase that acts as a key negative regulator of the Wnt signaling pathway by specifically mediating depalmitoleylation of WNT proteins. Serine palmitoleylation of WNT proteins is required for efficient binding to frizzled receptors (PubMed:25731175).
Cellular Location Secreted {ECO:0000250|UniProtKB:Q9VUX3}.
Tissue Location Rarely expressed in adult normal tissues.
Research Areas
Citations (0)

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NOTUM may deacetylate GlcNAc residues on cell surface glycans (Potential).


Torisu, Y., et al. Cancer Sci. 99(6):1139-1146(2008)
Lamesch, P., et al. Genomics 89(3):307-315(2007)

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Cat# AP17837b
(40 western blots)
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