|Application ||WB, E|
|Calculated MW||35376 Da|
|Antigen Region||246-273 aa|
|Other Names||Olfactory receptor 2C3, Olfactory receptor 2C4, Olfactory receptor 2C5, Olfactory receptor OR1-30, OR2C3, OR2C4, OR2C5P|
|Target/Specificity||This OR2C3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 246-273 amino acids from the C-terminal region of human OR2C3.|
|Precautions||OR2C3 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Cellular Location||Cell membrane; Multi-pass membrane protein.|
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Provided below are standard protocols that you may find useful for product applications.
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.
Trevino, L.R., et al. Nat. Genet. 41(9):1001-1005(2009)
Malnic, B., et al. Proc. Natl. Acad. Sci. U.S.A. 101(8):2584-2589(2004)
Fuchs, T., et al. Genomics 80(3):295-302(2002)
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