RG9MTD2 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
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Primary Accession | Q8TBZ6 |
Other Accession | NP_001128137.1 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 39719 Da |
Antigen Region | 199-225 aa |
Gene ID | 93587 |
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Other Names | tRNA methyltransferase 10 homolog A, 211-, RNA (guanine-9-)-methyltransferase domain-containing protein 2, TRMT10A, RG9MTD2 |
Target/Specificity | This RG9MTD2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 199-225 amino acids from the Central region of human RG9MTD2. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | RG9MTD2 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | TRMT10A |
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Synonyms | RG9MTD2 |
Function | S-adenosyl-L-methionine-dependent guanine N(1)- methyltransferase that catalyzes the formation of N(1)-methylguanine at position 9 (m1G9) in tRNAs (PubMed:23042678, PubMed:25053765). Probably not able to catalyze formation of N(1)-methyladenine at position 9 (m1A9) in tRNAs (PubMed:23042678). |
Cellular Location | Nucleus. Nucleus, nucleolus |
Tissue Location | Expressed in embryonic and fetal brain. It is expressed throughout the dorsal telencephalon at 8 and 11 weeks of gestation, with highest expression in ventricular zone and marginal zone. Detected in cerebellar cortex and nuclei, but not in dorsal telencephalon, at later stages. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Probable RNA methyltransferase (By similarity).
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