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>   home   >   Products   >   Primary Antibodies   >   Cell Biology   >   ANAPC4 Antibody (Center)   

ANAPC4 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - ANAPC4 Antibody (Center) AP17878c
    ANAPC4 Antibody (Center) (Cat. #AP17878c) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the ANAPC4 antibody detected the ANAPC4 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9UJX5
Other Accession NP_037499.2
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 92116 Da
Antigen Region 638-664 aa
Additional Information
Gene ID 29945
Other Names Anaphase-promoting complex subunit 4, APC4, Cyclosome subunit 4, ANAPC4, APC4
Target/Specificity This ANAPC4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 638-664 amino acids from the Central region of human ANAPC4.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsANAPC4 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms APC4
Function Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
Research Areas
Citations (0)

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A large protein complex, termed the anaphase-promoting complex (APC), or the cyclosome, promotes metaphase-anaphase transition by ubiquitinating its specific substrates such as mitotic cyclins and anaphase inhibitor, which are subsequently degraded by the 26S proteasome. Biochemical studies have shown that the vertebrate APC contains eight subunits. The composition of the APC is highly conserved in organisms from yeast to humans. The exact function of this gene product is not known. [provided by RefSeq].


Wasch, R., et al. Oncogene 29(1):1-10(2010)
Jin, L., et al. Cell 133(4):653-665(2008)
Nature 447(7145):661-678(2007)
Dube, P., et al. Mol. Cell 20(6):867-879(2005)
Listovsky, T., et al. EMBO J. 23(7):1619-1626(2004)

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$ 295.00
$ 99.00
Cat# AP17878c
(40 western blots)
Availability: In Stock
Bulk Size
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