FSCB Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
---|---|
Primary Accession | Q5H9T9 |
Other Accession | NP_115511.3 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 87956 Da |
Antigen Region | 794-823 aa |
Gene ID | 84075 |
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Other Names | Fibrous sheath CABYR-binding protein, FSCB, C14orf155 |
Target/Specificity | This FSCB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 794-823 amino acids from the C-terminal region of human FSCB. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | FSCB Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | FSCB |
---|---|
Synonyms | C14orf155 |
Function | May be involved in the later stages of fibrous sheath biogenesis and spermatozoa capacitation. Inhibits ROPN1 and ROPN1L SUMOylation. Binds calcium. |
Cellular Location | Cell projection, cilium, flagellum {ECO:0000250|UniProtKB:A1EGX6}. Note=Localizes to cortex of the fibrous sheath including the surface of the longitudinal columns and ribs of the principal piece of sperm flagella. {ECO:0000250|UniProtKB:A1EGX6} |
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Provided below are standard protocols that you may find useful for product applications.
Background
FSCB may be involved in the later stages of fibrous sheath biogenesis. Binds calcium (By similarity).
References
Li, Y.F., et al. J. Biol. Chem. 282(47):34104-34119(2007)
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