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RAB40A Antibody (Center)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - RAB40A Antibody (Center) AP17918c
    RAB40A Antibody (Center) (Cat. #AP17918c) western blot analysis in A2058 cell line lysates (35ug/lane).This demonstrates the RAB40A antibody detected the RAB40A protein (arrow).
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q8WXH6
Other Accession P0C0E4, NP_543155.2
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 31076 Da
Antigen Region 91-118 aa
Additional Information
Gene ID 142684
Other Names Ras-related protein Rab-40A, SOCS box-containing protein RAR2A, Protein Rar-2, RAB40A
Target/Specificity This RAB40A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 91-118 amino acids from the Central region of human RAB40A.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsRAB40A Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name RAB40A
Function May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
Cellular Location Cell membrane; Lipid-anchor; Cytoplasmic side
Research Areas
Citations (0)
citation

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Background

This gene encodes a member of the Rab40 subfamily of Rab small GTP-binding proteins that contains a C-terminal suppressors of cytokine signaling box.

References

Itoh, T., et al. Genes Cells 11(9):1023-1037(2006)
Fukuda, M. J. Biol. Chem. 278(17):15373-15380(2003)
Kile, B.T., et al. Trends Biochem. Sci. 27(5):235-241(2002)
Kuroda, T.S., et al. J. Biol. Chem. 277(11):9212-9218(2002)
Pereira-Leal, J.B., et al. J. Mol. Biol. 313(4):889-901(2001)

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$ 182.50
$ 70.00
Cat# AP17918c
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