|Application ||WB, E|
|Other Accession||P0C0E4, NP_543155.2|
|Calculated MW||31076 Da|
|Antigen Region||91-118 aa|
|Other Names||Ras-related protein Rab-40A, SOCS box-containing protein RAR2A, Protein Rar-2, RAB40A|
|Target/Specificity||This RAB40A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 91-118 amino acids from the Central region of human RAB40A.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||RAB40A Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.|
|Cellular Location||Cell membrane; Lipid-anchor; Cytoplasmic side|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a member of the Rab40 subfamily of Rab small GTP-binding proteins that contains a C-terminal suppressors of cytokine signaling box.
Itoh, T., et al. Genes Cells 11(9):1023-1037(2006)
Fukuda, M. J. Biol. Chem. 278(17):15373-15380(2003)
Kile, B.T., et al. Trends Biochem. Sci. 27(5):235-241(2002)
Kuroda, T.S., et al. J. Biol. Chem. 277(11):9212-9218(2002)
Pereira-Leal, J.B., et al. J. Mol. Biol. 313(4):889-901(2001)
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