|Application ||WB, E|
|Calculated MW||23554 Da|
|Antigen Region||71-97 aa|
|Other Names||Syntaxin-binding protein 6, Amisyn, STXBP6|
|Target/Specificity||This STXBP6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 71-97 amino acids from the Central region of human STXBP6.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||STXBP6 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Forms non-fusogenic complexes with SNAP25 and STX1A and may thereby modulate the formation of functional SNARE complexes and exocytosis.|
|Cellular Location||Cytoplasm. Membrane; Peripheral membrane protein|
|Tissue Location||Detected at low levels in brain, and at very low levels in heart, adrenal gland, testis, liver and kidney|
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Provided below are standard protocols that you may find useful for product applications.
STXBP6 binds components of the SNARE complex (see MIM 603215) and may be involved in regulating SNARE complex formation (Scales et al., 2002 [PubMed 12145319]).
Rose, J. Phd, et al. Mol. Med. (2010) In press :
Heilig, R., et al. Nature 421(6923):601-607(2003)
Scales, S.J., et al. J. Biol. Chem. 277(31):28271-28279(2002)
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