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ACCN5 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q9NY37 |
| Other Accession | NP_059115.1 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 57464 Da |
| Antigen Region | 388-414 aa |
| Gene ID | 51802 |
|---|---|
| Other Names | Acid-sensing ion channel 5, ASIC5, Amiloride-sensitive cation channel 5, Human intestine Na(+) channel, HINaC, ASIC5, ACCN5, HINAC |
| Target/Specificity | This ACCN5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 388-414 amino acids from the C-terminal region of human ACCN5. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | ACCN5 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | ASIC5 |
|---|---|
| Synonyms | ACCN5, HINAC |
| Function | Cation channel that gives rise to very low constitutive currents in the absence of activation. The activated channel exhibits selectivity for sodium, and is inhibited by amiloride. |
| Cellular Location | Cell membrane; Multi-pass membrane protein |
| Tissue Location | Detected in small intestine, duodenum and jejunum. Detected at very low levels in testis and rectum |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene belongs to the amiloride-sensitive Na+ channel and degenerin (NaC/DEG) family, members of which have been identified in many animal species ranging from the nematode to human. The amiloride-sensitive Na(+) channel encoded by this gene is primarily expressed in the small intestine, however, its exact function is not known.
References
Schaefer, L., et al. FEBS Lett. 471 (2-3), 205-210 (2000) :
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