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ABO Antibody (N-term)Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| AP17996a | 0.1 mg 400 ul | In Stock | $ 255.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
| AP17996a-ev20 | 20 ug 100 ul | In Stock | $ 95.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
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ABO Antibody (N-term) - Product info | |
| Application | WB
|
| Primary Accession | P16442 |
| Other Accession | NP_065202.2 |
| Reactivity | Human |
| Concentration | 0.25 mg/ml |
| Isotype | Rabbit Ig |
| Calculated MW | 40934 Da |
ABO Antibody (N-term) - Additional info | |
| Gene ID 28 | |
| Other Names ABO; Histo-blood group ABO system transferase; Fucosylglycoprotein 3-alpha-galactosyltransferase; Fucosylglycoprotein alpha-N-acetylgalactosaminyltransferase; Glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase; Glycoprotein-fucosylgalactoside alpha-galactosyltransferase; Histo-blood group A transferase; Histo-blood group B transferase; NAGAT; Fucosylglycoprotein alpha-N-acetylgalactosaminyltransferase soluble form | |
| Target/Specificity This ABO antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 40-68 amino acids from the N-terminal region of human ABO. | |
| Dilution WB~~1:100~500WB~~1:1000 | |
| Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions ABO Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. | |
ABO Antibody (N-term) - Protein Information | |
| Name ABO | |
| Function This protein is the basis of the ABO blood group system. The histo-blood group ABO involves three carbohydrate antigens: A, B, and H. A, B, and AB individuals express a glycosyltransferase activity that converts the H antigen to the A antigen (by addition of UDP-GalNAc) or to the B antigen (by addition of UDP-Gal), whereas O individuals lack such activity | |
| Cellular Location Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Secreted. Note=Membrane- bound form in trans cisternae of Golgi. Secreted into the body fluid | |
ABO Antibody (N-term) - Related products
AM2158a: ABO Antibody (N-term) (Ascites)
ABO Antibody (N-term) - Application data
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ABO Antibody (N-term) (Cat. #AP17996a) western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the ABO antibody detected the ABO protein (arrow).
ABO Antibody (N-term) - Research Areas
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BACKGROUND
This gene encodes proteins related to the first discovered blood group system, ABO. Which allele is present in an individual determines the blood group. The 'O' blood group is caused by a deletion of guanine-258 near the N-terminus of the protein which results in a frameshift and translation of an almost entirely different protein. Individuals with the A, B, and AB alleles express glycosyltransferase activities that convert the H antigen into the A or B antigen. Other minor alleles have been found for this gene.
REFERENCES
Thuresson, B., et al. Transfusion 48(3):493-504(2008) Seltsam, A., et al. Transfusion 47(12):2330-2335(2007) Twu, Y.C., et al. Transfusion 46(11):1988-1996(2006) Jenkins, P.V., et al. Transfusion 46(10):1836-1844(2006) Roubinet, F., et al. Transfusion 44(5):707-715(2004)
