|Application ||WB, E|
|Calculated MW||46106 Da|
|Antigen Region||279-308 aa|
|Other Names||Reticulon-4 receptor-like 2, Nogo receptor-like 3, Nogo-66 receptor homolog 1, Nogo-66 receptor-related protein 2, NgR2, RTN4RL2 (HGNC:23053)|
|Target/Specificity||This R4RL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 279-308 amino acids from the C-terminal region of human R4RL2.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||R4RL2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May play a role in regulating axonal regeneration and plasticity in the adult central nervous system.|
|Cellular Location||Cell membrane; Lipid-anchor, GPI-anchor Note=Localized to the surface of neurons, including axons|
|Tissue Location||Highly expressed in brain and liver. Expressed at lower levels in kidney, mammary gland, placenta, skeletal muscle, spleen and thyroid.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
RTN4RL2 may play a role in regulating axonal regeneration and plasticity in the adult central nervous system.
Lee, H., et al. J. Neurosci. 28(11):2753-2765(2008)
Taylor, T.D., et al. Nature 440(7083):497-500(2006)
Walmsley, A.R., et al. Biochem. Biophys. Res. Commun. 327(1):112-116(2005)
Lauren, J., et al. Mol. Cell. Neurosci. 24(3):581-594(2003)
Barton, W.A., et al. EMBO J. 22(13):3291-3302(2003)
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