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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   HHIP Antibody (N-term)   

HHIP Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - HHIP Antibody (N-term) AP18055A
    HHIP Antibody (N-term) (Cat. #AP18055a) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the HHIP antibody detected the HHIP protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q96QV1
Other Accession Q7TN16, NP_071920.1
Reactivity Human
Predicted Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 78851 Da
Antigen Region 25-54 aa
Additional Information
Gene ID 64399
Other Names Hedgehog-interacting protein, HHIP, HIP, HHIP, HIP
Target/Specificity This HHIP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 25-54 amino acids from the N-terminal region of human HHIP.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsHHIP Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms HIP
Function Modulates hedgehog signaling in several cell types including brain and lung through direct interaction with members of the hedgehog family.
Cellular Location Cell membrane; Peripheral membrane protein. Secreted. Note=The last 22 C-terminal amino acids may participate in cell membrane attachment
Tissue Location Widely expressed in fetal and adult tissues. Highest expression in adult heart, liver and pancreas, and in fetal kidney. {ECO:0000269|PubMed:11435703, ECO:0000269|Ref.1}
Research Areas
Citations (0)

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This gene encodes a protein similar to the mouse hedgehog-interacting protein, a regulatory component of the hedgehog signalling pathway. Members of the hedgehog family are evolutionarily conserved proteins which are involved in many fundamental processes in embryonic development, including anteroposterior patterns of limbs and regulation of left-right asymmetry.


Pillai, S.G., et al. Am. J. Respir. Crit. Care Med. (2010) In press :
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Liu, J.Z., et al. Twin Res Hum Genet 13(2):179-193(2010)
Cho, M.H., et al. Nat. Genet. 42(3):200-202(2010)
Zhao, J., et al. BMC Med. Genet. 11, 96 (2010) :

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Cat# AP18055A
(40 western blots)
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