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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   Mouse Stk24 Antibody (Center)   

Mouse Stk24 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - Mouse Stk24 Antibody (Center) AP18059c
    Mouse Stk24 Antibody (Center) (Cat. #AP18059c) western blot analysis in SK-BR-3 cell line lysates (35ug/lane).This demonstrates the Stk24 antibody detected the Stk24 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q99KH8
Other Accession Q9Y6E0, NP_663440.1
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 47954 Da
Antigen Region 222-249 aa
Additional Information
Gene ID 223255
Other Names Serine/threonine-protein kinase 24, Mammalian STE20-like protein kinase 3, MST-3, STE20-like kinase MST3, Serine/threonine-protein kinase 24 35 kDa subunit, Mammalian STE20-like protein kinase 3 N-terminal, MST3/N, Serine/threonine-protein kinase 24 12 kDa subunit, Mammalian STE20-like protein kinase 3 C-terminal, MST3/C, Stk24, Mst3, Stk3
Target/Specificity This Mouse Stk24 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 222-249 amino acids from the Central region of mouse Stk24.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsMouse Stk24 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Stk24
Synonyms Mst3, Stk3
Function Serine/threonine-protein kinase that acts on both serine and threonine residues and promotes apoptosis in response to stress stimuli and caspase activation. Mediates oxidative-stress- induced cell death by modulating phosphorylation of JNK1-JNK2 (MAPK8 and MAPK9), p38 (MAPK11, MAPK12, MAPK13 and MAPK14) during oxidative stress. Plays a role in a staurosporine-induced caspase- independent apoptotic pathway by regulating the nuclear translocation of AIFM1 and ENDOG and the DNase activity associated with ENDOG. Phosphorylates STK38L on 'Thr-442' and stimulates its kinase activity. Regulates cellular migration with alteration of PTPN12 activity and PXN phosphorylation: phosphorylates PTPN12 and inhibits its activity and may regulate PXN phosphorylation through PTPN12. Acts as a key regulator of axon regeneration in the optic nerve and radial nerve (By similarity).
Cellular Location Cytoplasm. Nucleus. Membrane. Note=The truncated form (MST3/N) translocates to the nucleus. Colocalizes with STK38L in the membrane (By similarity).
Research Areas
Citations (0)

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Protein kinase that act on both serine and threonine residues (By similarity).


Taniwaki, T., et al. Dev. Growth Differ. 47(3):163-172(2005)
Shu, H., et al. Mol. Cell Proteomics 3(3):279-286(2004)
Zambrowicz, B.P., et al. Proc. Natl. Acad. Sci. U.S.A. 100(24):14109-14114(2003)
Piao, Y., et al. Genome Res. 11(9):1553-1558(2001)
Araki, K., et al. Cell. Mol. Biol. (Noisy-le-grand) 45(5):737-750(1999)

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$ 295.00
$ 99.00
Cat# AP18059c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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