|Application ||WB, E|
|Calculated MW||49009 Da|
|Antigen Region||87-114 aa|
|Other Names||RNA-binding protein Nova-2, Astrocytic NOVA1-like RNA-binding protein, Neuro-oncological ventral antigen 2, NOVA2, ANOVA, NOVA3|
|Target/Specificity||This NOVA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 87-114 amino acids from the N-terminal region of human NOVA2.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||NOVA2 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May regulate RNA splicing or metabolism in a specific subset of developing neurons (By similarity). Binds single strand RNA.|
|Tissue Location||Brain. Expression restricted to astrocytes.|
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Provided below are standard protocols that you may find useful for product applications.
NOVA2 may regulate RNA splicing or metabolism in a specific subset of developing neurons (By similarity). Binds single strand RNA.
Heinzen, E.L., et al. Am. J. Hum. Genet. 80(5):876-883(2007)
Grimwood, J., et al. Nature 428(6982):529-535(2004)
Lewis, H.A., et al. Cell 100(3):323-332(2000)
Lewis, H.A., et al. Structure 7(2):191-203(1999)
Yang, Y.Y., et al. Proc. Natl. Acad. Sci. U.S.A. 95(22):13254-13259(1998)
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