|Application ||WB, E|
|Calculated MW||71713 Da|
|Antigen Region||645-673 aa|
|Other Names||Vasorin, Protein slit-like 2, VASN, SLITL2|
|Target/Specificity||This VASN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 645-673 amino acids from the C-terminal region of human VASN.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||VASN Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May act as an inhibitor of TGF-beta signaling.|
|Cellular Location||Membrane; Single-pass type I membrane protein Secreted|
|Tissue Location||Expressed at highest levels in aorta, at intermediate levels in kidney and placenta and at lowest levels in brain, heart, liver, lung and skeletal muscle. Within the aorta, the strongest expression is found in the tunica media of the proximal ascending aorta, the descending thoracic aorta, the abdominal aorta and the coronary arteries. Within the kidney, expression is found in the interstitial cells|
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Provided below are standard protocols that you may find useful for product applications.
VASN may act as an inhibitor of TGF-beta signaling.
Liu, T., et al. J. Proteome Res. 4(6):2070-2080(2005)
Ikeda, Y., et al. Proc. Natl. Acad. Sci. U.S.A. 101(29):10732-10737(2004)
Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003)
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