|Application ||WB, E|
|Calculated MW||27552 Da|
|Antigen Region||58-87 aa|
|Other Names||Homeobox protein VENTX, VENT homeobox homolog, VENT-like homeobox protein 2, VENTX, HPX42B, VENTX2|
|Target/Specificity||This VENTX antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 58-87 amino acids from the Central region of human VENTX.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||VENTX Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May be involved in ventralization.|
|Tissue Location||Expressed in bone marrow of patients recovering from chemotherapy. Also expressed in an erythroleukemia cell line.|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a member of the Vent family of homeodomain proteins. The encoded protein may function as a transcriptional repressor and be involved in mesodermal patterning and hemopoietic stem cell maintenance. Multiple pseudogenes exist for this gene. A transcribed pseudogene located on chromosome X may lead to antigen production in certain melanomas. [provided by RefSeq].
Rawat, V.P., et al. Proc. Natl. Acad. Sci. U.S.A. 107(39):16946-16951(2010)
Gao, H., et al. Cancer Res. 70(1):202-211(2010)
Holland, P.W., et al. BMC Biol. 5, 47 (2007) :
Moretti, P.A., et al. Genomics 76 (1-3), 21-29 (2001) :
Moreau-Aubry, A., et al. J. Exp. Med. 191(9):1617-1624(2000)
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