VENTX Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
---|---|
Primary Accession | O95231 |
Other Accession | NP_055283.1 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 27552 Da |
Antigen Region | 58-87 aa |
Gene ID | 27287 |
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Other Names | Homeobox protein VENTX, VENT homeobox homolog, VENT-like homeobox protein 2, VENTX, HPX42B, VENTX2 |
Target/Specificity | This VENTX antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 58-87 amino acids from the Central region of human VENTX. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | VENTX Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | VENTX |
---|---|
Synonyms | HPX42B, VENTX2 |
Function | May be involved in ventralization. |
Cellular Location | Nucleus. |
Tissue Location | Expressed in bone marrow of patients recovering from chemotherapy. Also expressed in an erythroleukemia cell line |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a member of the Vent family of homeodomain proteins. The encoded protein may function as a transcriptional repressor and be involved in mesodermal patterning and hemopoietic stem cell maintenance. Multiple pseudogenes exist for this gene. A transcribed pseudogene located on chromosome X may lead to antigen production in certain melanomas. [provided by RefSeq].
References
Rawat, V.P., et al. Proc. Natl. Acad. Sci. U.S.A. 107(39):16946-16951(2010)
Gao, H., et al. Cancer Res. 70(1):202-211(2010)
Holland, P.W., et al. BMC Biol. 5, 47 (2007) :
Moretti, P.A., et al. Genomics 76 (1-3), 21-29 (2001) :
Moreau-Aubry, A., et al. J. Exp. Med. 191(9):1617-1624(2000)
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