|Application ||WB, E|
|Other Accession||Q96DS6, NP_071744.2|
|Calculated MW||26943 Da|
|Antigen Region||11-38 aa|
|Other Names||Membrane-spanning 4-domains subfamily A member 6A, CD20 antigen-like 3, Four-span transmembrane protein 3, MS4A6A, 4SPAN3, CD20L3, MS4A6|
|Target/Specificity||This MS4A6A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 11-38 amino acids from the N-terminal region of human MS4A6A.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||MS4A6A Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||4SPAN3, CD20L3, MS4A6|
|Function||May be involved in signal transduction as a component of a multimeric receptor complex.|
|Cellular Location||Membrane; Multi-pass membrane protein.|
|Tissue Location||Variable expression in some B-cell, myelomonocytic, and erythroleukemia cell lines|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. The gene encoding this protein is localized to 11q12.1, among a cluster of family members. Alternative splicing of this gene results in several transcript variants.
Liu, C.Y., et al. Carcinogenesis 31(7):1259-1263(2010)
Davila, S., et al. Genes Immun. 11(3):232-238(2010)
Liang, Y., et al. Immunogenetics 53(5):357-368(2001)
Liang, Y., et al. Genomics 72(2):119-127(2001)
Ishibashi, K., et al. Gene 264(1):87-93(2001)
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