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SLN13 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q68D06 |
| Other Accession | NP_653283.3 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 102045 Da |
| Antigen Region | 632-663 aa |
| Gene ID | 146857 |
|---|---|
| Other Names | Schlafen family member 13, SLFN13 |
| Target/Specificity | This SLN13 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 632-663 amino acids from the C-terminal region of human SLN13. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | SLN13 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | SLFN13 (HGNC:26481) |
|---|---|
| Function | Endoribonuclease that cleaves tRNAs and rRNAs (PubMed:29563550). Cleaves tRNAs 11 nucleotides from the 3'-terminus at the acceptor stem (PubMed:29563550). Does not act on tRNA(Sec) (PubMed:29563550). Able to restrict HIV-1 virus replication; ability to inhibit HIV-1 replication is dependent on endoribonuclease activity (PubMed:29563550). |
| Cellular Location | Cytoplasm. |
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Provided below are standard protocols that you may find useful for product applications.
Background
SLFN13 belongs to the Schlafen family.
References
Schwarz, D.A., et al. Immunity 9(5):657-668(1998)
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