|Application ||WB, E|
|Calculated MW||43448 Da|
|Antigen Region||85-114 aa|
|Other Names||Protein TFG, TRK-fused gene protein, TFG|
|Target/Specificity||This TFG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 85-114 amino acids from the Central region of human TFG.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||TFG Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Plays a role in the normal dynamic function of the endoplasmic reticulum (ER) and its associated microtubules.|
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Provided below are standard protocols that you may find useful for product applications.
There are several documented fusion oncoproteins encoded partially by this gene. This gene also participates in several oncogenic rearrangements resulting in anaplastic lymphoma and mixoid chondrosarcoma, and may play a role in the NF-kappaB pathway. Multiple transcript variants have been found for this gene.
Miranda, C., et al. J. Cell. Physiol. 208(1):154-160(2006)
Roccato, E., et al. J. Biol. Chem. 280(5):3382-3389(2005)
Hisaoka, M., et al. Genes Chromosomes Cancer 40(4):325-328(2004)
Roccato, E., et al. Br. J. Cancer 87(6):645-653(2002)
Hernandez, L., et al. Am. J. Pathol. 160(4):1487-1494(2002)
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