|Application ||WB, E|
|Calculated MW||80558 Da|
|Antigen Region||511-539 aa|
|Other Names||N-acetylated-alpha-linked acidic dipeptidase-like protein, NAALADase L, 100 kDa ileum brush border membrane protein, I100, Ileal dipeptidylpeptidase, NAALADL1, NAALADASEL, NAALADL|
|Target/Specificity||This NAALADL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 511-539 amino acids from the C-terminal region of human NAALADL1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||NAALADL1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||NAALADase-like activity unknown. Has no NAAG hydrolyzing activity. Exhibits a dipeptidyl-peptidase IV type activity. In vitro, cleaves Gly-Pro-AMC (By similarity).|
|Cellular Location||Apical cell membrane; Single-pass type II membrane protein. Note=Ileal brush border membrane|
|Tissue Location||Mainly expressed in the distal small intestine. Also expressed in the spleen and testis. Weak expression in the brain, locating mainly to the brain stem, amygdala, thalamus and ventral striatum. Isoform 2 and 3 isoform 3 are found in the small intestine and colon|
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Provided below are standard protocols that you may find useful for product applications.
NAALADase-like activity unknown. It has no NAAG hydrolyzing activity. Exhibits a dipeptidyl-peptidase IV type activity. In vitro, cleaves Gly-Pro-AMC (By similarity).
Pangalos, M.N., et al. J. Biol. Chem. 274(13):8470-8483(1999)
Shneider, B.L., et al. J. Biol. Chem. 272(49):31006-31015(1997)
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