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OTUD7A Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| IHC-P-Leica, WB, E |
|---|---|
| Primary Accession | Q8TE49 |
| Other Accession | NP_570971.1 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 100677 Da |
| Antigen Region | 70-99 aa |
| Gene ID | 161725 |
|---|---|
| Other Names | OTU domain-containing protein 7A, Zinc finger protein Cezanne 2, OTUD7A, C15orf16, CEZANNE2, OTUD7 |
| Target/Specificity | This OTUD7A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 70-99 amino acids from the N-terminal region of human OTUD7A. |
| Dilution | WB~~1:1000 IHC-P-Leica~~1:100 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | OTUD7A Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | OTUD7A |
|---|---|
| Synonyms | C15orf16, CEZANNE2, OTUD7 |
| Function | Has deubiquitinating activity towards 'Lys-11'-linked polyubiquitin chains. |
| Cellular Location | Cytoplasm. Nucleus. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Deubiquitinating enzymes (DUBs; see MIM 603478) are proteases that specifically cleave ubiquitin (MIM 191339) linkages, negating the action of ubiquitin ligases. OTUD7A belongs to a DUB subfamily characterized by an ovarian tumor (OTU) domain.[supplied by OMIM].
References
Morrison, A.C., et al. Circ Cardiovasc Genet 3(3):248-255(2010)
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