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KCNK12 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q9HB15 |
| Other Accession | NP_071338.1 |
| Reactivity | Human, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 46889 Da |
| Antigen Region | 335-364 aa |
| Gene ID | 56660 |
|---|---|
| Other Names | Potassium channel subfamily K member 12, Tandem pore domain halothane-inhibited potassium channel 2, THIK-2, KCNK12 |
| Target/Specificity | This KCNK12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 335-364 amino acids from the C-terminal region of human KCNK12. |
| Dilution | WB~~1:2000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | KCNK12 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | KCNK12 |
|---|---|
| Function | Probable potassium channel subunit. No channel activity observed in heterologous systems. May need to associate with another protein to form a functional channel (By similarity). |
| Cellular Location | Membrane; Multi-pass membrane protein |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. The product of this gene has not been shown to be a functional channel, however, it may require other non-pore-forming proteins for activity.
References
Birlea, S.A., et al. J. Invest. Dermatol. 130(3):798-803(2010)
Nyholt, D.R., et al. Hum. Mol. Genet. 17(21):3318-3331(2008)
Theilig, F., et al. Cell. Physiol. Biochem. 21 (1-3), 63-74 (2008) :
Olsen, J.V., et al. Cell 127(3):635-648(2006)
Olsen, J.V., et al. Cell 127(3):635-648(2006)
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