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BPHL Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - BPHL Antibody (Center) AP18229C
    BPHL Antibody (Center) (Cat. #AP18229c) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the BPHL antibody detected the BPHL protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q86WA6
Other Accession NP_004323.2
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 32543 Da
Antigen Region 96-124 aa
Additional Information
Gene ID 670
Other Names Valacyclovir hydrolase, VACVase, Valacyclovirase, 31--, Biphenyl hydrolase-like protein, Biphenyl hydrolase-related protein, Bph-rp, Breast epithelial mucin-associated antigen, MCNAA, BPHL, MCNAA
Target/Specificity This BPHL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 96-124 amino acids from the Central region of human BPHL.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsBPHL Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms MCNAA
Function Serine hydrolase that catalyzes the hydrolytic activation of amino acid ester prodrugs of nucleoside analogs such as valacyclovir and valganciclovir. Activates valacyclovir to acyclovir. May play a role in detoxification processes. It is a specific alpha-amino acid ester hydrolase that prefers small, hydrophobic, and aromatic side chains and does not have a stringent requirement for the leaving group other than preferring a primary alcohol.
Tissue Location Expressed at high levels in liver and kidney and lower levels in heart, intestine and skeletal muscle
Research Areas
Citations (0)

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This gene encodes a member of the serine protease family of hydrolytic enzymes which contain a serine in their active site. The encoded protein may play a role in activation of the antiviral prodrug valacyclovir. Alternatively spliced transcript variants have been described.


Davila, S., et al. Genes Immun. 11(3):232-238(2010)
Lai, L., et al. J. Biol. Chem. 283(14):9318-9327(2008)
Grigo, K., et al. Biol. Chem. 389(2):179-187(2008)
Melk, A., et al. Kidney Int. 68(6):2667-2679(2005)
Kim, I., et al. Mol. Pharm. 1(6):434-446(2004)

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$ 295.00
$ 99.00
Cat# AP18229C
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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