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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   GNPTG Antibody (C-term)   

GNPTG Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - GNPTG Antibody (C-term) AP18233b
    GNPTG Antibody (C-term) (Cat. #AP18233b) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the GNPTG antibody detected the GNPTG protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9UJJ9
Other Accession NP_115909.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 33974 Da
Antigen Region 266-296 aa
Additional Information
Gene ID 84572
Other Names N-acetylglucosamine-1-phosphotransferase subunit gamma, GlcNAc-1-phosphotransferase subunit gamma, UDP-N-acetylglucosamine-1-phosphotransferase subunit gamma, GNPTG, C16orf27, GNPTAG
Target/Specificity This GNPTG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 266-296 amino acids from the C-terminal region of human GNPTG.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGNPTG Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms C16orf27, GNPTAG
Function Non-catalytic subunit of the N-acetylglucosamine-1- phosphotransferase complex, an enzyme that catalyzes the formation of mannose 6-phosphate (M6P) markers on high mannose type oligosaccharides in the Golgi apparatus. Binds and presents the high mannose glycans of the acceptor to the catalytic alpha and beta subunits (GNPTAB). Enhances the rate of N-acetylglucosamine- 1-phosphate transfer to the oligosaccharides of acid hydrolase acceptors.
Cellular Location Secreted. Golgi apparatus
Tissue Location Widely expressed.
Research Areas
Citations (0)

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This gene encodes the gamma sunbunit of the N-acetylglucosamine-1-phosphotransferase complex. This hexameric complex, composed of alpha, beta and gamma subunits, catalyzes the first step in synthesis of a mannose 6-phosphate lysosomal recognition marker. This enzyme complex is necessary for targeting of lysosomal hydrolases to the lysosome. Mutations in the gene encoding the gamma subunit have been associated with mucolipidosis IIIC, also known as mucolipidosis III gamma.


Kang, C., et al. N. Engl. J. Med. 362(8):677-685(2010)
Qian, Y., et al. J. Biol. Chem. 285(5):3360-3370(2010)
Pohl, S., et al. Am. J. Med. Genet. A 152A (1), 124-132 (2010) :
Encarnacao, M., et al. Clin. Genet. 76(1):76-84(2009)
Persichetti, E., et al. Hum. Mutat. 30(6):978-984(2009)

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$ 295.00
$ 99.00
Cat# AP18233b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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