MBD3L1 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
---|---|
Primary Accession | Q8WWY6 |
Other Accession | NP_660209.2 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 21616 Da |
Antigen Region | 168-194 aa |
Gene ID | 85509 |
---|---|
Other Names | Methyl-CpG-binding domain protein 3-like 1, MBD3-like protein 1, MBD3L1, MBD3L |
Target/Specificity | This MBD3L1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 168-194 amino acids from the C-terminal region of human MBD3L1. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | MBD3L1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | MBD3L1 |
---|---|
Synonyms | MBD3L |
Function | Transcriptional repressor. |
Cellular Location | Nucleus. Note=Nuclear, in large foci |
Tissue Location | Highly expressed in testis. Detected at low levels in pancreas. Not detected in the other tissues tested |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a protein that is related to methyl-CpG-binding proteins but lacks the methyl-CpG binding domain. The protein is localized to discrete areas in the nucleus, and expression appears to be restricted to round spermatids, suggesting that the protein plays a role in the postmeiotic stages of male germ cell development.
References
Jiang, C.L., et al. J. Biol. Chem. 279(50):52456-52464(2004)
Yao, Y.L., et al. J. Biol. Chem. 278(43):42560-42568(2003)
Jiang, C.L., et al. Genomics 80(6):621-629(2002)
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