|Application ||WB, E|
|Calculated MW||21616 Da|
|Antigen Region||168-194 aa|
|Other Names||Methyl-CpG-binding domain protein 3-like 1, MBD3-like protein 1, MBD3L1, MBD3L|
|Target/Specificity||This MBD3L1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 168-194 amino acids from the C-terminal region of human MBD3L1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||MBD3L1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Cellular Location||Nucleus. Note=Nuclear, in large foci|
|Tissue Location||Highly expressed in testis. Detected at low levels in pancreas. Not detected in the other tissues tested|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a protein that is related to methyl-CpG-binding proteins but lacks the methyl-CpG binding domain. The protein is localized to discrete areas in the nucleus, and expression appears to be restricted to round spermatids, suggesting that the protein plays a role in the postmeiotic stages of male germ cell development.
Jiang, C.L., et al. J. Biol. Chem. 279(50):52456-52464(2004)
Yao, Y.L., et al. J. Biol. Chem. 278(43):42560-42568(2003)
Jiang, C.L., et al. Genomics 80(6):621-629(2002)
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