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MBD3L1 Antibody (C-term)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - MBD3L1 Antibody (C-term) AP18250b
    MBD3L1 Antibody (C-term) (Cat. #AP18250b) western blot analysis in A375 cell line lysates (35ug/lane).This demonstrates the MBD3L1 antibody detected the MBD3L1 protein (arrow).
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q8WWY6
Other Accession NP_660209.2
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 21616 Da
Antigen Region 168-194 aa
Additional Information
Gene ID 85509
Other Names Methyl-CpG-binding domain protein 3-like 1, MBD3-like protein 1, MBD3L1, MBD3L
Target/Specificity This MBD3L1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 168-194 amino acids from the C-terminal region of human MBD3L1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsMBD3L1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name MBD3L1
Synonyms MBD3L
Function Transcriptional repressor.
Cellular Location Nucleus. Note=Nuclear, in large foci
Tissue Location Highly expressed in testis. Detected at low levels in pancreas. Not detected in the other tissues tested
Citations (0)
citation

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Background

This gene encodes a protein that is related to methyl-CpG-binding proteins but lacks the methyl-CpG binding domain. The protein is localized to discrete areas in the nucleus, and expression appears to be restricted to round spermatids, suggesting that the protein plays a role in the postmeiotic stages of male germ cell development.

References

Jiang, C.L., et al. J. Biol. Chem. 279(50):52456-52464(2004)
Yao, Y.L., et al. J. Biol. Chem. 278(43):42560-42568(2003)
Jiang, C.L., et al. Genomics 80(6):621-629(2002)

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$ 182.50
$ 70.00
Cat# AP18250b
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