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>   home   >   Products   >   Primary Antibodies   >   DUS2L Antibody (C-term)   

DUS2L Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - DUS2L Antibody (C-term) AP18265b
    DUS2L Antibody (C-term) (Cat. #AP18265b) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the DUS2L antibody detected the DUS2L protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9NX74
Other Accession NP_060273.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 55050 Da
Antigen Region 371-397 aa
Additional Information
Gene ID 54920
Other Names tRNA-dihydrouridine(20) synthase [NAD(P)+]-like, 131-, Dihydrouridine synthase 2, Up-regulated in lung cancer protein 8, URLC8, tRNA-dihydrouridine synthase 2-like, hDUS2, DUS2, DUS2L
Target/Specificity This DUS2L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 371-397 amino acids from the C-terminal region of human DUS2L.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsDUS2L Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name DUS2
Synonyms DUS2L
Function Dihydrouridine synthase. Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs. Negatively regulates the activation of EIF2AK2/PKR.
Cellular Location Cytoplasm. Endoplasmic reticulum. Note=Mainly at the endoplasmic reticulum
Tissue Location Weak expression in heart, placenta and skeletal muscle. Up-regulated in most lung cancer cells (at protein level).
Citations (0)

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Dihydrouridine synthase catalyzes reduction of the 5,6-double bond of a uridine residue on the displacement loop of tRNA. The resultant modified base, 5,6-dihydrouridine, appears to increase the conformational flexibility and dynamic motion of tRNA (Kato et al., 2005 [PubMed 15994936]).


Mittelstadt, M., et al. Nucleic Acids Res. 36(3):998-1008(2008)
Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007)
Lamesch, P., et al. Genomics 89(3):307-315(2007)
Kato, T., et al. Cancer Res. 65(13):5638-5646(2005)

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$ 295.00
$ 99.00
Cat# AP18265b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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