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AMBRA1 Antibody (N-term)Purified Rabbit Polyclonal Antibody (Pab)

Country
United States
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Ordering Information
Catalog # Size Availability Price  
AP1826a 0.1 mg 400 ul In Stock $ 255.00 Add to cart
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AMBRA1 Antibody (N-term) - Product info

ApplicationWB, IHC
  • Applications Legend:
  • W=Western Blotting
  • IP=Immunoprecipitation
  • IHC-P=Immunohistochemistry (Paraffin)
  • IF-IC=Immunofluorescence (Immunocytochemistry)
  • F=Flow Cytometry
Primary AccessionQ9C0C7
Other AccessionA2AH22
ReactivityHuman
PredictedMouse
Concentration0.25 mg/ml
IsotypeRabbit Ig
Calculated MW142507 Da

AMBRA1 Antibody (N-term) - Additional info

Gene ID 55626
Other Names
AMBRA1; KIAA1736; Activating molecule in BECN1-regulated autophagy protein 1
Target/Specificity
This AMBRA1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human AMBRA1.
Dilution
WB~~1:50~100
IHC~~1:10~50
Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Storage
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Precautions
AMBRA1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.

AMBRA1 Antibody (N-term) - Protein Information

Name AMBRA1
Synonyms KIAA1736
Function
Regulates autophagy and development of the nervous system. Involved in autophagy in controlling protein turnover during neuronal development, and in regulating normal cell survival and proliferation (By similarity)
Cellular Location
Cytoplasmic vesicle, autophagosome (By similarity)

AMBRA1 Antibody (N-term) - Related products

AP1826a: AMBRA1 Antibody (N-term)

RI10268: AMBRA1 predesign siRNA

BP1826a: AMBRA1 Antibody (N-term) Blocking Peptide

AMBRA1 Antibody (N-term) - Application data

  • Western blot analysis of AMBRA1 Antibody (N-term) in HepG2 cell line lysates (35ug/lane). AMBRA1(arrow) was detected using the purified Pab (1:60 dilution).

  • Formalin-fixed and paraffin-embedded human breast carcinoma tissue reacted with AMBRA1 antibody (N-term) (Cat.#AP1826a), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

AMBRA1 Antibody (N-term) - Research Areas

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BACKGROUND

AMBRA1 regulates autophagy and development of the nervous system. This protein is involved in autophagy in controlling protein turnover during neuronal development, and in regulating normal cell survival and proliferation.

REFERENCES

Maria Fimia G.,Nature 447:1121-1125(2007). Nagase T.,DNA Res. 7:347-355(2000). Ota T.,Nat. Genet. 36:40-45(2004).