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TRNAU1AP Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q9NX07 |
| Other Accession | Q9QZI7, Q80VC6, Q1RMJ7, NP_060316.1 |
| Reactivity | Human |
| Predicted | Bovine, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 32499 Da |
| Antigen Region | 160-186 aa |
| Gene ID | 54952 |
|---|---|
| Other Names | tRNA selenocysteine 1-associated protein 1, SECp43, tRNA selenocysteine-associated protein 1, TRNAU1AP, SECP43, TRSPAP1 |
| Target/Specificity | This TRNAU1AP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 160-186 amino acids from the Central region of human TRNAU1AP. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | TRNAU1AP Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | TRNAU1AP |
|---|---|
| Synonyms | SECP43, TRSPAP1 |
| Function | Involved in the early steps of selenocysteine biosynthesis and tRNA(Sec) charging to the later steps resulting in the cotranslational incorporation of selenocysteine into selenoproteins. Stabilizes the SECISBP2, EEFSEC and tRNA(Sec) complex. May be involved in the methylation of tRNA(Sec). Enhances efficiency of selenoproteins synthesis (By similarity). |
| Cellular Location | Nucleus. Cytoplasm. Note=Abundant in the nucleus. |
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Provided below are standard protocols that you may find useful for product applications.
Background
TRNAU1AP is involved in the early steps of selenocysteine biosynthesis and tRNA(Sec) charging to the later steps resulting in the cotranslational incorporation of selenocysteine into selenoproteins. Stabilizes the SECISBP2, EEFSEC and tRNA(Sec) complex. May be involved in the methylation of tRNA(Sec). Enhances efficiency of selenoproteins synthesis (By similarity).
References
Small-Howard, A., et al. Mol. Cell. Biol. 26(6):2337-2346(2006)
Xu, X.M., et al. J. Biol. Chem. 280(50):41568-41575(2005)
Ding, F., et al. RNA 5(12):1561-1569(1999)
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