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ADNP Antibody (C-term)Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| AP18350b | 0.1 mg 400 ul | In Stock | $ 255.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
| AP18350b-ev20 | Ev20 size 100 ul | In Stock | $ 95.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
- Specification
- Citiations : 0
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- Backgrounds
ADNP Antibody (C-term) - Product info | |
| Application | WB
|
| Primary Accession | Q9H2P0 |
| Other Accession | Q9Z103, NP_852107.1 |
| Reactivity | Human, Mouse |
| Concentration | 0.25 mg/ml |
| Isotype | Rabbit Ig |
| Calculated MW | 123563 Da |
ADNP Antibody (C-term) - Additional info | |
| Gene ID 23394 | |
| Other Names ADNP; ADNP1; KIAA0784; Activity-dependent neuroprotector homeobox protein; Activity-dependent neuroprotective protein | |
| Target/Specificity This ADNP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 830-860 amino acids from the C-terminal region of human ADNP. | |
| Dilution WB~~1:100~500WB~~1:1000 | |
| Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions ADNP Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. | |
ADNP Antibody (C-term) - Protein Information | |
| Name ADNP | |
| Synonyms ADNP1, KIAA0784 | |
| Function Potential transcription factor. May mediate some of the neuroprotective peptide VIP-associated effects involving normal growth and cancer proliferation | |
| Cellular Location Nucleus (Potential). | |
| Tissue Location Widely expressed. Strong expression in heart, skeletal muscle, kidney and placenta. In brain, expression is stronger in the cerebellum and cortex regions. No expression detected in the colon. Strong increase of expression in colon and breast cancer tissues | |
ADNP Antibody (C-term) - Related products
ADNP Antibody (C-term) - Application data
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ADNP Antibody (C-term) (Cat. #AP18350b) western blot analysis in mouse NIH-3T3 cell line lysates (35ug/lane).This demonstrates the ADNP Antibody detected the ADNP protein (arrow).
ADNP Antibody (C-term) - Research Areas
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BACKGROUND
Vasoactive intestinal peptide is a neuroprotective factor that has a stimulatory effect on the growth of some tumor cells and an inhibitory effect on others. This gene encodes a protein that is upregulated by vasoactive intestinal peptide and may be involved in its stimulatory effect on certain tumor cells. The encoded protein contains one homeobox and nine zinc finger domains, suggesting that it functions as a transcription factor. This gene is also upregulated in normal proliferative tissues. Finally, the encoded protein may increase the viability of certain cell types through modulation of p53 activity. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq].
REFERENCES
Braitch, M., et al. Neuroimmunomodulation 17(2):120-125(2010) Mandel, S., et al. J. Biol. Chem. 282(47):34448-34456(2007) Wu, C., et al. Proteomics 7(11):1775-1785(2007) Matsuoka, S., et al. Science 316(5828):1160-1166(2007) Kankova, K., et al. Diabetologia 50(5):990-999(2007)
