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ABCC9 Antibody (Center)Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| AP18353c | 0.1 mg 400 ul | In Stock | $ 255.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
| AP18353c-ev20 | 20 ug 100 ul | In Stock | $ 95.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
- Specification
- Citiations : 0
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ABCC9 Antibody (Center) - Product info | |
| Application | WB
|
| Primary Accession | O60706 |
| Other Accession | NP_005682.2 |
| Reactivity | Human, Mouse |
| Concentration | 0.25 mg/ml |
| Isotype | Rabbit Ig |
| Calculated MW | 174223 Da |
ABCC9 Antibody (Center) - Additional info | |
| Gene ID 10060 | |
| Other Names ABCC9; SUR2; ATP-binding cassette sub-family C member 9; Sulfonylurea receptor 2 | |
| Target/Specificity This ABCC9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 639-669 amino acids from the Central region of human ABCC9. | |
| Dilution WB~~1:100~500WB~~1:1000 | |
| Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions ABCC9 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. | |
ABCC9 Antibody (Center) - Protein Information | |
| Name ABCC9 | |
| Synonyms SUR2 | |
| Function Subunit of ATP-sensitive potassium channels (KATP). Can form cardiac and smooth muscle-type KATP channels with KCNJ11 KCNJ11 forms the channel pore while ABCC9 is required for activation and regulation | |
| Cellular Location Membrane; Multi-pass membrane protein (Potential) | |
ABCC9 Antibody (Center) - Related products
ABCC9 Antibody (Center) - Application data
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ABCC9 Antibody (Center) (Cat. #AP18353c) western blot analysis in mouse kidney tissue lysates (35ug/lane).This demonstrates the ABCC9 Antibody detected the ABCC9 protein (arrow).
ABCC9 Antibody (Center) - Research Areas
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BACKGROUND
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein is thought to form ATP-sensitive potassium channels in cardiac, skeletal, and vascular and non-vascular smooth muscle. Protein structure suggests a role as the drug-binding channel-modulating subunit of the extrapancreatic ATP-sensitive potassium channels. No disease has been associated with this gene thus far. Alternative splicing of this gene results in several products, two of which result from differential usage of two terminal exons and one of which results from exon deletion.
REFERENCES
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010) Zimmerman, R.S., et al. Genet. Med. 12(5):268-278(2010) Ellis, J.A., et al. Physiol. Genomics 40(3):184-188(2010) Kim, S.J., et al. Biochem. Biophys. Res. Commun. 391(1):974-978(2010) Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
