|Application ||WB, E|
|Calculated MW||77727 Da|
|Antigen Region||196-223 aa|
|Other Names||Protein-arginine deiminase type-6, Peptidyl arginine deiminase-like protein, Peptidylarginine deiminase VI, hPADVI, Protein-arginine deiminase type VI, PADI6|
|Target/Specificity||This PADI6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 196-223 amino acids from the N-terminal region of human PADI6.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||PADI6 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Catalyzes the deimination of arginine residues of proteins. May be involved in cytoskeletal reorganization in the egg and early embryo (By similarity).|
|Cellular Location||Cytoplasm. Nucleus|
|Tissue Location||Ovary, testis and peripheral blood leukocytes.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Peptidylarginine deiminases (PADs, EC 22.214.171.124), including PADI6, make up a family of posttranslational protein modification enzymes that convert arginine residues to citrulline residues in the presence of calcium ions.
Stacey, S.N., et al. Nat. Genet. 40(11):1313-1318(2008)
Chavanas, S., et al. Gene 330, 19-27 (2004) :
Zhang, J., et al. Acta Biochim. Pol. 51(4):1051-1058(2004)
Vossenaar, E.R., et al. Bioessays 25(11):1106-1118(2003)
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