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SSX3 Antibody (Center)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - SSX3 Antibody (Center) AP18393c
    SSX3 Antibody (Center) (Cat. #AP18393c) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the SSX3 Antibody detected the SSX3 protein (arrow).
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q99909
Other Accession NP_066294.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 21697 Da
Antigen Region 53-80 aa
Additional Information
Gene ID 10214
Other Names Protein SSX3, Cancer/testis antigen 53, CT53, SSX3
Target/Specificity This SSX3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 53-80 amino acids from the Central region of human SSX3.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsSSX3 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SSX3
Function Could act as a modulator of transcription.
Citations (0)
citation

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Background

The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneously humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. SSX1, SSX2 and SSX4 genes have been involved in the t(X;18) translocation characteristically found in all synovial sarcomas. This gene appears not to be involved in this type of chromosome translocation. Two transcript variants encoding distinct isoforms have been identified for this gene.

References

Ross, M.T., et al. Nature 434(7031):325-337(2005)
Gure, A.O., et al. Int. J. Cancer 101(5):448-453(2002)
de Bruijn, D.R., et al. Genes Chromosomes Cancer 34(3):285-298(2002)
Gure, A.O., et al. Int. J. Cancer 72(6):965-971(1997)
de Leeuw, B., et al. Cytogenet. Cell Genet. 73(3):179-183(1996)

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$ 182.50
$ 70.00
Cat# AP18393c
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