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WFIKKN2 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q8TEU8 |
| Other Accession | NP_783165.1 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 63941 Da |
| Antigen Region | 535-564 aa |
| Gene ID | 124857 |
|---|---|
| Other Names | WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2, Growth and differentiation factor-associated serum protein 1, GASP-1, hGASP-1, WAP, follistatin, immunoglobulin, Kunitz and NTR domain-containing-related protein, WFIKKN-related protein, WFIKKN2, GASP1, WFIKKNRP |
| Target/Specificity | This WFIKKN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 535-564 amino acids from the C-terminal region of human WFIKKN2. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | WFIKKN2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | WFIKKN2 |
|---|---|
| Synonyms | GASP1, WFIKKNRP |
| Function | Protease-inhibitor that contains multiple distinct protease inhibitor domains. Probably has serine protease- and metalloprotease- inhibitor activity. Inhibits the biological activity of mature myostatin, but not activin (By similarity). |
| Cellular Location | Secreted. |
| Tissue Location | Primarily expressed in ovary, testis and brain, but not in liver. In fetal tissues, it is primarily expressed in brain, skeletal muscle, thymus and kidney. |
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Provided below are standard protocols that you may find useful for product applications.
Background
The WFIKKN1 protein contains a WAP domain, follistatin domain, immunoglobulin domain, two tandem Kunitz domains, and an NTR domain. This gene encodes a WFIKKN1-related protein which has the same domain organization as the WFIKKN1 protein. The WAP-type, follistatin type, Kunitz-type, and NTR-type protease inhibitory domains may control the action of multiple types of proteases.
References
Saremi, A., et al. Mol. Cell. Endocrinol. 317 (1-2), 25-30 (2010) :
Kondas, K., et al. J. Biol. Chem. 283(35):23677-23684(2008)
Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003)
Hill, J.J., et al. Mol. Endocrinol. 17(6):1144-1154(2003)
Nagy, A., et al. Eur. J. Biochem. 270(9):2101-2107(2003)
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