|Application ||WB, E|
|Calculated MW||63941 Da|
|Antigen Region||535-564 aa|
|Other Names||WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2, Growth and differentiation factor-associated serum protein 1, GASP-1, hGASP-1, WAP, follistatin, immunoglobulin, Kunitz and NTR domain-containing-related protein, WFIKKN-related protein, WFIKKN2, GASP1, WFIKKNRP|
|Target/Specificity||This WFIKKN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 535-564 amino acids from the C-terminal region of human WFIKKN2.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||WFIKKN2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Protease-inhibitor that contains multiple distinct protease inhibitor domains. Probably has serine protease- and metalloprotease-inhibitor activity. Inhibits the biological activity of mature myostatin, but not activin (By similarity).|
|Tissue Location||Primarily expressed in ovary, testis and brain, but not in liver. In fetal tissues, it is primarily expressed in brain, skeletal muscle, thymus and kidney|
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Provided below are standard protocols that you may find useful for product applications.
The WFIKKN1 protein contains a WAP domain, follistatin domain, immunoglobulin domain, two tandem Kunitz domains, and an NTR domain. This gene encodes a WFIKKN1-related protein which has the same domain organization as the WFIKKN1 protein. The WAP-type, follistatin type, Kunitz-type, and NTR-type protease inhibitory domains may control the action of multiple types of proteases.
Saremi, A., et al. Mol. Cell. Endocrinol. 317 (1-2), 25-30 (2010) :
Kondas, K., et al. J. Biol. Chem. 283(35):23677-23684(2008)
Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003)
Hill, J.J., et al. Mol. Endocrinol. 17(6):1144-1154(2003)
Nagy, A., et al. Eur. J. Biochem. 270(9):2101-2107(2003)
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