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MEOX2 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • IF - MEOX2 Antibody (Center) AP18398C
    Fluorescent image of NIH-3T3 cell stained with MEOX2 Antibody (Center)(Cat#AP18398c).NIH-3T3 cells were fixed with 4% PFA (20 min), permeabilized with Triton X-100 (0.1%, 10 min), then incubated with MEOX2 primary antibody (1:25, 1 h at 37℃). For secondary antibody, Alexa Fluor® 488 conjugated donkey anti-rabbit antibody (green) was used (1:400, 50 min at 37℃).Cytoplasmic actin was counterstained with Alexa Fluor® 555 (red) conjugated Phalloidin (7units/ml, 1 h at 37℃).MEOX2 immunoreactivity is localized to Nucleus significantly.
  • WB - MEOX2 Antibody (Center) AP18398C
    MEOX2 Antibody (Center) (Cat. #AP18398c) western blot analysis in MDA-MB453 cell line lysates (35ug/lane).This demonstrates the MEOX2 Antibody detected the MEOX2 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P50222
Other Accession P39020, P32443, NP_005915.2
Reactivity Human
Predicted Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 33594 Da
Antigen Region 164-192 aa
Additional Information
Gene ID 4223
Other Names Homeobox protein MOX-2, Growth arrest-specific homeobox, Mesenchyme homeobox 2, MEOX2, GAX, MOX2
Target/Specificity This MEOX2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 164-192 amino acids from the Central region of human MEOX2.
Dilution IF~~1:10~50
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsMEOX2 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name MEOX2
Synonyms GAX, MOX2
Function Mesodermal transcription factor that plays a key role in somitogenesis and is required for sclerotome development (By similarity). Activates expression of CDKN1A and CDKN2A in endothelial cells, acting as a regulator of vascular cell proliferation. While it activates CDKN1A in a DNA-dependent manner, it activates CDKN2A in a DNA-independent manner (PubMed:22206000). May have a regulatory role when quiescent vascular smooth muscle cells reenter the cell cycle.
Cellular Location Nucleus. Nucleus speckle {ECO:0000255|PROSITE-ProRule:PRU00108, ECO:0000269|PubMed:19266028}
Tissue Location Embryo and placenta.
Research Areas
Citations (0)

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This gene encodes a member of a subfamily of non-clustered, diverged, antennapedia-like homeobox-containing genes. The encoded protein may play a role in the regulation of vertebrate limb myogenesis. Mutations in the related mouse protein may be associated with craniofacial and/or skeletal abnormalities, in addition to neurovascular dysfunction observed in Alzheimer's disease.


Rose, J. Phd, et al. Mol. Med. (2010) In press :
Ohshima, J., et al. Genes Chromosomes Cancer 48(12):1037-1050(2009)
Irelan, J.T., et al. PLoS ONE 4 (4), E5067 (2009) :
Chen, Y., et al. Blood 111(3):1217-1226(2008)
Valcourt, U., et al. Mol Oncol 1(1):55-71(2007)

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$ 295.00
$ 99.00
Cat# AP18398C
(40 western blots)
Availability: In Stock
Bulk Size
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