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SEPSECS Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

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Ordering Information
Catalog # SizeAvailability Price  
AP18403b 400 µl
(40 western blots)
In Stock $ 265.00 Add to cart
AP18403b-ev 80 µl
(8 western blots)
In Stock $ 95.00 Add to cart
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SEPSECS Antibody (C-term) - Product Information

  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • ICC=Immunocytochemistry
  • CHIP=Chromatin Immunoprecipitation
  • IHCF=Immunohistochemistry (Frozen Sections)
  • FA=Fluorescence Assay
  • IHCP=Immunohistochemistry (Paraffin-embedded Sections)
  • IC=Immunochemistry
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary AccessionQ9HD40
Other AccessionNP_058651.3
Isotype Rabbit Ig
Calculated MW 55726 Da
Antigen Region 444-474 aa

SEPSECS Antibody (C-term) - Additional Information

Gene ID 51091
Other Names
O-phosphoseryl-tRNA(Sec) selenium transferase, Liver-pancreas antigen, LP, SLA-p35, SLA/LP autoantigen, Selenocysteine synthase, Sec synthase, Selenocysteinyl-tRNA(Sec) synthase, Sep-tRNA:Sec-tRNA synthase, SepSecS, Soluble liver antigen, SLA, UGA suppressor tRNA-associated protein, tRNA(Ser/Sec)-associated antigenic protein, SEPSECS, TRNP48
This SEPSECS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 444-474 amino acids from the C-terminal region of human SEPSECS.
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
SEPSECS Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.

SEPSECS Antibody (C-term) - Protein Information

Synonyms TRNP48
Converts O-phosphoseryl-tRNA(Sec) to selenocysteinyl- tRNA(Sec) required for selenoprotein biosynthesis.
Cellular Location
Tissue Location
Primarily expressed in liver, pancreas, kidney and lung. Overexpressed in PHA-stimulated T-cells

SEPSECS Antibody (C-term) - Related Products

BP18403b: SEPSECS Antibody (C-term) Blocking Peptide

SEPSECS Antibody (C-term) - Research Areas

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Provided below are standard protocols that you may find useful for product applications.


The 21st amino acid, selenocysteine (sec), is distinct from other amino acids because it lacks its own tRNA synthetase and is the only amino acid synthesized on its cognate tRNA. Synthesis of sec begins with acylation of tRNA(sec) (TRSP; MIM 165060) by seryl-tRNA synthetase (SARS; MIM 607529) to give ser-tRNA(sec), which is subsequently phosphorylated by O-phosphoseryl-tRNA kinase (PSTK; MIM 611310) to give O-phosphoseryl-tRNA(sec). SEPSECS catalyzes the final step of sec synthesis by converting O-phosphoseryl-tRNA(sec) to selenocysteinyl-tRNA(sec) using selenophosphate as the selenium donor (Palioura et al., 2009 [PubMed 19608919]).


Agamy, O., et al. Am. J. Hum. Genet. 87(4):538-544(2010)
Hart, K., et al. Lung Cancer (2010) In press :
Volkmann, M., et al. J. Autoimmun. 34(1):59-65(2010)
Palioura, S., et al. Science 325(5938):321-325(2009)
Xu, X.M., et al. PLoS Biol. 5 (1), E4 (2007) :