|Application ||WB, E|
|Other Accession||Q64119, P60662, Q60605, P60661, P14649, NP_066299.2|
|Predicted||Bovine, Mouse, Pig, Rat|
|Calculated MW||16930 Da|
|Antigen Region||32-59 aa|
|Other Names||Myosin light polypeptide 6, 17 kDa myosin light chain, LC17, Myosin light chain 3, MLC-3, Myosin light chain alkali 3, Myosin light chain A3, Smooth muscle and nonmuscle myosin light chain alkali 6, MYL6|
|Target/Specificity||This MYL6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 32-59 amino acids from the Central region of human MYL6.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||MYL6 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Regulatory light chain of myosin. Does not bind calcium.|
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Provided below are standard protocols that you may find useful for product applications.
Myosin is a hexameric ATPase cellular motor protein. It is composed of two heavy chains, two nonphosphorylatable alkali light chains, and two phosphorylatable regulatory light chains. This gene encodes a myosin alkali light chain that is expressed in smooth muscle and non-muscle tissues. Genomic sequences representing several pseudogenes have been described and two transcript variants encoding different isoforms have been identified for this gene.
Rikova, K., et al. Cell 131(6):1190-1203(2007)
Lamesch, P., et al. Genomics 89(3):307-315(2007)
Fu, Z.Y., et al. Acta Biochim. Biophys. Sin. (Shanghai) 38(9):625-632(2006)
Rush, J., et al. Nat. Biotechnol. 23(1):94-101(2005)
Webb, R.C. Adv Physiol Educ 27 (1-4), 201-206 (2003) :
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