|Application ||WB, E|
|Calculated MW||34803 Da|
|Antigen Region||209-236 aa|
|Other Names||rRNA/tRNA 2'-O-methyltransferase fibrillarin-like protein 1, 211-, Protein-glutamine methyltransferase, FBLL1|
|Target/Specificity||This FBLL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 209-236 amino acids from the Central region of human FBLL1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||FBLL1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||S-adenosyl-L-methionine-dependent methyltransferase that has the ability to methylate both RNAs and proteins. Involved in pre-rRNA processing by catalyzing the site-specific 2'-hydroxyl methylation of ribose moieties in pre-ribosomal RNA. Also acts as a protein methyltransferase by mediating methylation of glutamine residues (By similarity).|
|Cellular Location||Nucleus, nucleolus. Note=Fibrillar region of the nucleolus.|
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Provided below are standard protocols that you may find useful for product applications.
FBLL1 is involved in pre-rRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in pre-ribosomal RNA (By similarity).
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