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FCRL1 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q96LA6 |
| Other Accession | NP_001152869.1 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 46936 Da |
| Antigen Region | 366-392 aa |
| Gene ID | 115350 |
|---|---|
| Other Names | Fc receptor-like protein 1, FcR-like protein 1, FcRL1, Fc receptor homolog 1, FcRH1, IFGP family protein 1, hIFGP1, Immune receptor translocation-associated protein 5, CD307a, FCRL1, FCRH1, IFGP1, IRTA5 |
| Target/Specificity | This FCRL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 366-392 amino acids from the C-terminal region of human FCRL1. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | FCRL1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | FCRL1 |
|---|---|
| Synonyms | FCRH1, IFGP1, IRTA5 |
| Function | May function as an activating coreceptor in B-cells. May function in B-cells activation and differentiation. |
| Cellular Location | Cell membrane; Single-pass type I membrane protein |
| Tissue Location | Primarily expressed in secondary lymphoid tissues by mature subsets of B-cells. Detected in spleen, lymph node, heart, skeletal muscle, kidney, liver and placenta. Specifically expressed by mature B lineage cells with higher expression in naive versus memory B- cells (at protein level). |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a member of the immunoglobulin receptor superfamily and is one of several Fc receptor-like glycoproteins clustered on the long arm of chromosome 1. The encoded protein contains three extracellular C2-like immunoglobulin domains, a transmembrane domain and a cytoplasmic domain with two immunoreceptor-tyrosine activation motifs. This protein may play a role in the regulation of cancer cell growth. Alternative splicing results in multiple transcript variants.
References
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Davila, S., et al. Genes Immun. 11(3):232-238(2010)
Kazemi, T., et al. Cancer Immunol. Immunother. 58(6):989-996(2009)
Kazemi, T., et al. Int. J. Cancer 123(9):2113-2119(2008)
Du, X., et al. Blood 111(1):338-343(2008)
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