SOHLH2 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
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Primary Accession | Q9NX45 |
Other Accession | NP_060296.2 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 46941 Da |
Antigen Region | 232-258 aa |
Gene ID | 100526761;54937 |
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Other Names | Spermatogenesis- and oogenesis-specific basic helix-loop-helix-containing protein 2, SOHLH2, TEB1 |
Target/Specificity | This SOHLH2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 232-258 amino acids from the Central region of human SOHLH2. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | SOHLH2 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | SOHLH2 |
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Synonyms | TEB1 |
Function | Transcription regulator of both male and female germline differentiation. Suppresses genes involved in spermatogonial stem cells maintenance, and induces genes important for spermatogonial differentiation. Coordinates oocyte differentiation without affecting meiosis I (By similarity). |
Cellular Location | Nucleus {ECO:0000250|UniProtKB:Q9D489, ECO:0000255|PROSITE-ProRule:PRU00981}. Cytoplasm {ECO:0000250|UniProtKB:Q9D489}. Note=Translocates from the cytoplasm into the nucleus and the translocation is dependent on SOHLH1 expression. {ECO:0000250|UniProtKB:Q9D489} |
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Provided below are standard protocols that you may find useful for product applications.
Background
Probable transcription factor, which may be involved in spermatogenesis and oogenesis (By similarity).
References
Wheeler, H.E., et al. PLoS Genet. 5 (10), E1000685 (2009) :
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