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SOHLH2 Antibody (Center)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - SOHLH2 Antibody (Center) AP18515c
    SOHLH2 Antibody (Center) (Cat. #AP18515c) western blot analysis in MDA-MB453 cell line lysates (35ug/lane).This demonstrates the SOHLH2 antibody detected the SOHLH2 protein (arrow).
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q9NX45
Other Accession NP_060296.2
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 46941 Da
Antigen Region 232-258 aa
Additional Information
Gene ID 100526761;54937
Other Names Spermatogenesis- and oogenesis-specific basic helix-loop-helix-containing protein 2, SOHLH2, TEB1
Target/Specificity This SOHLH2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 232-258 amino acids from the Central region of human SOHLH2.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsSOHLH2 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SOHLH2
Synonyms TEB1
Function Transcription regulator of both male and female germline differentiation. Suppresses genes involved in spermatogonial stem cells maintenance, and induces genes important for spermatogonial differentiation. Coordinates oocyte differentiation without affecting meiosis I (By similarity).
Cellular Location Nucleus {ECO:0000250|UniProtKB:Q9D489, ECO:0000255|PROSITE-ProRule:PRU00981}. Cytoplasm {ECO:0000250|UniProtKB:Q9D489}. Note=Translocates from the cytoplasm into the nucleus and the translocation is dependent on SOHLH1 expression. {ECO:0000250|UniProtKB:Q9D489}
Research Areas
Citations (0)
citation

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Background

Probable transcription factor, which may be involved in spermatogenesis and oogenesis (By similarity).

References

Wheeler, H.E., et al. PLoS Genet. 5 (10), E1000685 (2009) :

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$ 182.50
$ 70.00
Cat# AP18515c
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