|Application ||WB, E|
|Calculated MW||52605 Da|
|Antigen Region||69-95 aa|
|Other Names||Erythroid membrane-associated protein, hERMAP, Radin blood group antigen, Scianna blood group antigen, ERMAP, RD, SC|
|Target/Specificity||This ERMAP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 69-95 amino acids from the N-terminal region of human ERMAP.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||ERMAP Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Possible role as a cell-adhesion or receptor molecule of erythroid cells.|
|Cellular Location||Cell membrane; Single-pass type I membrane protein. Cytoplasm|
|Tissue Location||Expressed in erythroid-enriched bone marrow (at protein level). Highly expressed in bone marrow and to a lower extent in leukocytes, thymus, lymph node and spleen|
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Provided below are standard protocols that you may find useful for product applications.
The protein encoded by this gene is a cell surface transmembrane protein that may act as an erythroid cell receptor, possibly as a mediator of cell adhesion. Polymorphisms in this gene are responsible for the Scianna/Radin blood group system. Two transcript variants encoding the same protein have been found for this gene.
Fuchisawa, A., et al. Immunohematology 25(1):18-19(2009)
Lin, L.D., et al. Zhongguo Shi Yan Xue Ye Xue Za Zhi 16(2):328-332(2008)
Flegel, W.A., et al. Transfusion 45(12):1940-1944(2005)
Hue-Roye, K., et al. Transfusion 45(2):245-247(2005)
Yan, L., et al. Immunohematology 21(1):10-14(2005)
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