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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   HBS1L Antibody (Center)   

HBS1L Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - HBS1L Antibody (Center) AP18556C
    Anti-HBS1L Antibody (Center) at 1:2000 dilution + Jurkat whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 75 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
  • WB - HBS1L Antibody (Center) AP18556C
    Anti-HBS1L Antibody (Center) at 1:2000 dilution + Jurkat whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 75 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
  • WB - HBS1L Antibody (Center) AP18556C
    All lanes : Anti-HBS1L Antibody (Center) at 1:2000 dilution Lane 1: Human brain lysate Lane 2: Human heart lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 75 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
  • WB - HBS1L Antibody (Center) AP18556C
    HBS1L Antibody (Center) (Cat. #AP18556c) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the HBS1L antibody detected the HBS1L protein (arrow).
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q9Y450
Other Accession Q6AXM7, Q69ZS7, Q2KHZ2, NP_001138630.1
Reactivity Human, Mouse
Predicted Bovine, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 75473 Da
Antigen Region 460-486 aa
Additional Information
Gene ID 10767
Other Names HBS1-like protein, ERFS, HBS1L, HBS1, KIAA1038
Target/Specificity This HBS1L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 460-486 amino acids from the Central region of human HBS1L.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsHBS1L Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name HBS1L
Synonyms HBS1, KIAA1038
Tissue Location Detected in heart, brain, placenta, liver, muscle, kidney and pancreas.
Research Areas
Citations (0)

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Background

This gene encodes a member of the GTP-binding elongation factor family. It is expressed in multiple tissues with the highest expression in heart and skeletal muscle. The intergenic region of this gene and the MYB gene has been identified to be a quantitative trait locus (QTL) controlling fetal hemoglobin level, and this region influnces erythrocyte, platelet, and monocyte counts as well as erythrocyte volume and hemoglobin content. DNA polymorphisms at this region associate with fetal hemoglobin levels and pain crises in sickle cell disease. A single nucleotide polymorphism in exon 1 of this gene is significantly associated with severity in beta-thalassemia/Hemoglobin E. Multiple alternatively spliced transcript variants encoding different protein isoforms have been found for this gene.

References

Nuinoon, M., et al. Hum. Genet. 127(3):303-314(2010)
Kamatani, Y., et al. Nat. Genet. 42(3):210-215(2010)
Nuinoon, M., et al. Hum. Genet. (2009) In press :
Ganesh, S.K., et al. Nat. Genet. 41(11):1191-1198(2009)
Ferreira, M.A., et al. Am. J. Hum. Genet. 85(5):745-749(2009)

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$ 295.00
$ 99.00
Cat# AP18556C
Size:
Quantity:
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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