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>   home   >   Products   >   Primary Antibodies   >   Immunology   >   IL22RA2 Antibody (N-term)   

IL22RA2 Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - IL22RA2 Antibody (N-term) AP18561A
    IL22RA2 Antibody (N-term) (Cat. #AP18561a) western blot analysis in T47D cell line lysates (35ug/lane).This demonstrates the IL22RA2 antibody detected the IL22RA2 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q969J5
Other Accession NP_443194.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 30550 Da
Antigen Region 15-42 aa
Additional Information
Gene ID 116379
Other Names Interleukin-22 receptor subunit alpha-2, IL-22 receptor subunit alpha-2, IL-22R-alpha-2, IL-22RA2, Cytokine receptor class-II member 10, Cytokine receptor family 2 member 10, CRF2-10, Cytokine receptor family type 2, soluble 1, CRF2-S1, Interleukin-22-binding protein, IL-22BP, IL22BP, ZcytoR16, IL22RA2
Target/Specificity This IL22RA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 15-42 amino acids from the N-terminal region of human IL22RA2.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsIL22RA2 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name IL22RA2
Function Isoform 2 is a receptor for IL22. Binds to IL22, prevents interaction with the functional IL-22R complex and blocks the activity of IL22 (in vitro). May play an important role as an IL22 antagonist in the regulation of inflammatory responses.
Cellular Location Secreted.
Tissue Location Expressed in placenta, spleen, breast, skin and lung. Also detected in intestinal tract, testis, brain, heart and thymus. No expression found in prostate, bladder, kidney, ovary, muscle, bone marrow, liver and uterus. Isoform 1 is expressed only in placenta. Isoform 2 is expressed in placenta and breast and at lower level in spleen, skin, thymus and stomach
Research Areas
Citations (0)

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The protein encoded by this gene is a soluble class II cytokine receptor. This protein has been shown to specifically bind to interleukin 22 (IL22), block the interaction of IL22 with its cell surface receptor, and thus inhibit IL22 activity. This protein functions as an IL22 antagonist, and may be important in the regulation of inflammatory response. Three alternatively spliced transcript variants encoding distinct isoforms have been described.


Davila, S., et al. Genes Immun. 11(3):232-238(2010)
Kingo, K., et al. J. Dermatol. Sci. 57(1):71-73(2010)
Trynka, G., et al. Gut 58(8):1078-1083(2009)
Endam, L.M., et al. Otolaryngol Head Neck Surg 140(5):741-747(2009)
de Moura, P.R., et al. FEBS Lett. 583(7):1072-1077(2009)

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$ 295.00
$ 99.00
Cat# AP18561A
(40 western blots)
Availability: In Stock
Bulk Size
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