|Application ||WB, E|
|Other Accession||Q8VHQ4, NP_001166134.1|
|Calculated MW||31304 Da|
|Antigen Region||122-148 aa|
|Other Names||Ras-related protein Rab-40C, Rar-like protein, Ras-like protein family member 8C, SOCS box-containing protein RAR3, RAB40C, RARL, RASL8C|
|Target/Specificity||This RAB40C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 122-148 amino acids from the Central region of human RAB40C.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||RAB40C Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.|
|Cellular Location||Cell membrane; Lipid-anchor; Cytoplasmic side|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
Ng, E.L., et al. Brain Res Rev 58(1):236-246(2008)
Lettre, G., et al. Nat. Genet. 40(5):584-591(2008)
Martin, J., et al. Nature 432(7020):988-994(2004)
Kile, B.T., et al. Trends Biochem. Sci. 27(5):235-241(2002)
Pereira-Leal, J.B., et al. J. Mol. Biol. 313(4):889-901(2001)
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