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>   home   >   Products   >   Primary Antibodies   >   Cell Biology   >   MPPE1 Antibody (C-term)   

MPPE1 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - MPPE1 Antibody (C-term) AP18577b
    MPPE1 Antibody (C-term) (Cat. #AP18577b) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the MPPE1 antibody detected the MPPE1 protein (arrow).
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q53F39
Other Accession Q9GMS6, NP_075563.3
Reactivity Human
Predicted Monkey
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 45141 Da
Antigen Region 261-289 aa
Additional Information
Gene ID 65258
Other Names Metallophosphoesterase 1, 31--, Post-GPI attachment to proteins factor 5, MPPE1, PGAP5
Target/Specificity This MPPE1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 261-289 amino acids from the C-terminal region of human MPPE1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsMPPE1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name MPPE1
Synonyms PGAP5
Function Metallophosphoesterase required for transport of GPI- anchor proteins from the endoplasmic reticulum to the Golgi. Acts in lipid remodeling steps of GPI-anchor maturation by mediating the removal of a side-chain ethanolamine-phosphate (EtNP) from the second Man (Man2) of the GPI intermediate, an essential step for efficient transport of GPI-anchor proteins.
Cellular Location Endoplasmic reticulum-Golgi intermediate compartment membrane; Multi-pass membrane protein. Golgi apparatus, cis-Golgi network membrane; Multi- pass membrane protein. Note=Also localizes to endoplasmic reticulum exit site
Tissue Location Expressed in brain.
Research Areas
Citations (0)

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Background

Metallophosphoesterase required for transport of GPI-anchor proteins from the endoplasmic reticulum to the Golgi. Acts in lipid remodeling steps of GPI-anchor maturation by mediating the removal of a side-chain ethanolamine-phosphate (EtNP) from the second Man (Man2) of the GPI intermediate, an essential step for efficient transport of GPI-anchor proteins.

References

Lohoff, F.W., et al. Am. J. Med. Genet. B Neuropsychiatr. Genet. 153B (3), 830-836 (2010) :
Fujita, M., et al. Cell 139(2):352-365(2009)
Yosifova, A., et al. J Affect Disord 117 (1-2), 87-97 (2009) :
Fortna, A., et al. PLoS Biol. 2 (7), E207 (2004) :
Vuoristo, J.T., et al. Cytogenet. Cell Genet. 95 (1-2), 60-63 (2001) :

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$ 295.00
$ 99.00
Cat# AP18577b
Size:
Quantity:
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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